1-(3,5-Bis(trifluoromethyl)phenyl)-3-((S)-1-((R)-2-(4-chlorophenyl)-2-methylpyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)thiourea
95%
- Product Code: 233568
CAS:
2756689-44-6
| Molecular Weight: | 580.03 g./mol | Molecular Formula: | C₂₆H₂₈ClF₆N₃OS |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 556.8±60.0 °C(Predicted) | |
| Density: | 1.338±0.06 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Used as a potent antagonist in the development of pharmaceutical agents targeting inflammatory and autoimmune diseases. It shows high selectivity in modulating specific cytokine pathways, particularly involved in the inhibition of interleukin-17 production, making it valuable in research for conditions like psoriasis, multiple sclerosis, and rheumatoid arthritis. Its structure enables enhanced metabolic stability and bioavailability, which supports its use in preclinical studies for oral therapeutics. Also employed as a reference compound in receptor binding assays due to its strong affinity and stereochemical specificity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50mg | 10-20 days | ฿11,240.00 |
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| 100mg | 10-20 days | ฿17,970.00 |
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| 250mg | 10-20 days | ฿30,540.00 |
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1-(3,5-Bis(trifluoromethyl)phenyl)-3-((S)-1-((R)-2-(4-chlorophenyl)-2-methylpyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)thiourea
Used as a potent antagonist in the development of pharmaceutical agents targeting inflammatory and autoimmune diseases. It shows high selectivity in modulating specific cytokine pathways, particularly involved in the inhibition of interleukin-17 production, making it valuable in research for conditions like psoriasis, multiple sclerosis, and rheumatoid arthritis. Its structure enables enhanced metabolic stability and bioavailability, which supports its use in preclinical studies for oral therapeutics. Also employed as a reference compound in receptor binding assays due to its strong affinity and stereochemical specificity.
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