Selumetinib

10mM in DMSO

  • Product Code: 233834
  CAS:    606143-52-6
Molecular Weight: 457.69 g./mol Molecular Formula: C₁₇H₁₅BrClFN₄O₃
EC Number: MDL Number:
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Density: Storage Condition: -20°C
Product Description: Used primarily in the treatment of certain types of cancer, particularly neurofibromatosis type 1 (NF1) with inoperable plexiform neurofibromas in pediatric patients. It functions by inhibiting MEK, a key protein in the RAS/RAF/MEK/ERK signaling pathway, which is often overactive in cancers. By blocking this pathway, it helps slow or stop tumor growth. It is also investigated and applied in melanoma and non-small cell lung cancer where mutations in the pathway drive disease progression. Its oral formulation allows for outpatient treatment, improving patient convenience and quality of life.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1ml 10-20 days ฿8,360.00
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Selumetinib
Used primarily in the treatment of certain types of cancer, particularly neurofibromatosis type 1 (NF1) with inoperable plexiform neurofibromas in pediatric patients. It functions by inhibiting MEK, a key protein in the RAS/RAF/MEK/ERK signaling pathway, which is often overactive in cancers. By blocking this pathway, it helps slow or stop tumor growth. It is also investigated and applied in melanoma and non-small cell lung cancer where mutations in the pathway drive disease progression. Its oral formulation allows for outpatient treatment, improving patient convenience and quality of life.
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