SAR131675
10mM in DMSO
- Product Code: 233912
CAS:
1433953-83-3
| Molecular Weight: | 358.39 g./mol | Molecular Formula: | C₁₈H₂₂N₄O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD23098773 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
SAR131675 is primarily used in biomedical research as a selective antagonist of the chemokine receptor CXCR7. It is widely applied in studies related to cancer biology, where it helps modulate tumor cell signaling, migration, and survival pathways influenced by the CXCL12/CXCR7 axis. Researchers use SAR131675 to investigate the role of CXCR7 in tumor angiogenesis, metastasis, and tumor-stromal interactions, particularly in breast, prostate, and lung cancers.
In addition to oncology, SAR131675 serves as a tool compound in cardiovascular and inflammatory disease research. It aids in understanding how CXCR7 regulates cell adhesion, chemotaxis, and tissue regeneration. The compound is also employed in stem cell studies, where CXCR7 inhibition can influence stem cell homing and engraftment efficiency.
Due to its specificity and cell permeability, SAR131675 is valuable in in vitro and in vivo experimental models to dissect CXCR7-dependent mechanisms and evaluate potential therapeutic strategies targeting this receptor.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | $344.99 |
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SAR131675
SAR131675 is primarily used in biomedical research as a selective antagonist of the chemokine receptor CXCR7. It is widely applied in studies related to cancer biology, where it helps modulate tumor cell signaling, migration, and survival pathways influenced by the CXCL12/CXCR7 axis. Researchers use SAR131675 to investigate the role of CXCR7 in tumor angiogenesis, metastasis, and tumor-stromal interactions, particularly in breast, prostate, and lung cancers.
In addition to oncology, SAR131675 serves as a tool compound in cardiovascular and inflammatory disease research. It aids in understanding how CXCR7 regulates cell adhesion, chemotaxis, and tissue regeneration. The compound is also employed in stem cell studies, where CXCR7 inhibition can influence stem cell homing and engraftment efficiency.
Due to its specificity and cell permeability, SAR131675 is valuable in in vitro and in vivo experimental models to dissect CXCR7-dependent mechanisms and evaluate potential therapeutic strategies targeting this receptor.
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