SANT-1
10mM in DMSO
- Product Code: 234120
CAS:
304909-07-7
| Molecular Weight: | 373.49 g./mol | Molecular Formula: | C₂₃H₂₇N₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD01827306 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
SANT-1 is primarily used in research settings for its ability to modulate the Hedgehog (Hh) signaling pathway, a critical pathway involved in embryonic development and tissue homeostasis. It acts as a potent inhibitor of Smoothened (SMO), a key protein in the Hh pathway. Due to this inhibitory effect, SANT-1 is widely applied in studies related to cancer biology, particularly in investigating tumor types where the Hh pathway is abnormally activated, such as basal cell carcinoma and medulloblastoma.
Researchers use SANT-1 to probe the mechanisms of signal transduction in developmental biology and to evaluate potential therapeutic strategies for Hh-dependent cancers. Its selectivity and potency make it a valuable tool in high-throughput screening and structure-activity relationship (SAR) studies aimed at developing new anticancer agents. SANT-1 is not used clinically but remains important in preclinical research for validating targets and understanding pathway dynamics.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,590.00 |
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SANT-1
SANT-1 is primarily used in research settings for its ability to modulate the Hedgehog (Hh) signaling pathway, a critical pathway involved in embryonic development and tissue homeostasis. It acts as a potent inhibitor of Smoothened (SMO), a key protein in the Hh pathway. Due to this inhibitory effect, SANT-1 is widely applied in studies related to cancer biology, particularly in investigating tumor types where the Hh pathway is abnormally activated, such as basal cell carcinoma and medulloblastoma.
Researchers use SANT-1 to probe the mechanisms of signal transduction in developmental biology and to evaluate potential therapeutic strategies for Hh-dependent cancers. Its selectivity and potency make it a valuable tool in high-throughput screening and structure-activity relationship (SAR) studies aimed at developing new anticancer agents. SANT-1 is not used clinically but remains important in preclinical research for validating targets and understanding pathway dynamics.
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