(S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid
95%
- Product Code: 235074
CAS:
244132-27-2
| Molecular Weight: | 452.5 g./mol | Molecular Formula: | C₂₅H₂₈N₂O₆ |
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| Density: | Storage Condition: | Room temperature, dry |
Product Description:
Widely used in peptide synthesis and medicinal chemistry, this compound serves as a chiral building block for the preparation of complex molecules, especially those requiring stereochemical control. Its structure contains two protected functional groups—Fmoc and Boc—which allow for selective deprotection and stepwise assembly of peptides or peptidomimetics. The Fmoc group enables solid-phase peptide synthesis by providing reversible N-terminal protection that is easily removed under mild basic conditions, while the Boc group offers stability under these conditions and can be cleaved later under acidic conditions. This dual protection strategy makes the compound valuable in the synthesis of pharmaceutical intermediates, particularly in the development of bioactive peptides and small-molecule drugs targeting neurological disorders, cancer, and metabolic diseases. Its piperazine backbone also contributes to improved solubility and bioavailability in drug candidates, enhancing its utility in lead optimization during drug discovery.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿1,140.00 |
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| 250mg | 10-20 days | ฿2,690.00 |
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| 1g | 10-20 days | ฿9,030.00 |
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| 25g | 10-20 days | ฿128,000.00 |
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| 5g | 10-20 days | ฿38,400.00 |
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(S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid
Widely used in peptide synthesis and medicinal chemistry, this compound serves as a chiral building block for the preparation of complex molecules, especially those requiring stereochemical control. Its structure contains two protected functional groups—Fmoc and Boc—which allow for selective deprotection and stepwise assembly of peptides or peptidomimetics. The Fmoc group enables solid-phase peptide synthesis by providing reversible N-terminal protection that is easily removed under mild basic conditions, while the Boc group offers stability under these conditions and can be cleaved later under acidic conditions. This dual protection strategy makes the compound valuable in the synthesis of pharmaceutical intermediates, particularly in the development of bioactive peptides and small-molecule drugs targeting neurological disorders, cancer, and metabolic diseases. Its piperazine backbone also contributes to improved solubility and bioavailability in drug candidates, enhancing its utility in lead optimization during drug discovery.
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