(S)-N-FMOC-alpha-Methyl-2-fluorophenylalanine,
>97%
- Product Code: 235122
CAS:
1172127-44-4
| Molecular Weight: | 419.44 g./mol | Molecular Formula: | C₂₅H₂₂FNO₄ |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | Room temperature |
Product Description:
Used in peptide synthesis as a chiral building block for developing pharmaceuticals, particularly in creating enzyme inhibitors or bioactive peptides with enhanced metabolic stability. The FMOC group enables solid-phase peptide synthesis by providing orthogonal protection for the amine functionality. The alpha-methyl substitution restricts conformational flexibility, helping to stabilize specific peptide secondary structures like turns or helices. The fluorophenyl group improves lipophilicity and can enhance binding selectivity in receptor-targeted compounds. Commonly applied in medicinal chemistry for drug discovery, especially in CNS-targeted agents and protease-resistant peptide analogs.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿1,149.50 |
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| 1g | 10-20 days | ฿3,118.50 |
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(S)-N-FMOC-alpha-Methyl-2-fluorophenylalanine,
Used in peptide synthesis as a chiral building block for developing pharmaceuticals, particularly in creating enzyme inhibitors or bioactive peptides with enhanced metabolic stability. The FMOC group enables solid-phase peptide synthesis by providing orthogonal protection for the amine functionality. The alpha-methyl substitution restricts conformational flexibility, helping to stabilize specific peptide secondary structures like turns or helices. The fluorophenyl group improves lipophilicity and can enhance binding selectivity in receptor-targeted compounds. Commonly applied in medicinal chemistry for drug discovery, especially in CNS-targeted agents and protease-resistant peptide analogs.
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