(2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
98%
- Product Code: 235175
CAS:
1012341-52-4
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| Density: | Storage Condition: | Room temperature, dry |
Product Description:
Used as a key intermediate in the synthesis of protease inhibitors, particularly in the development of antiviral drugs such as those targeting hepatitis C virus (HCV). Its stereochemistry and functional groups allow for selective binding to enzyme active sites, enhancing drug efficacy. The Boc-protected amine facilitates stepwise peptide coupling in solid-phase or solution-phase synthesis, while the carboxylic acid and hydrophobic biphenyl group contribute to molecular recognition and stability. Commonly employed in medicinal chemistry for constructing complex peptidomimetic structures with improved metabolic resistance and bioavailability.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿7,310.00 |
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| 0.250 | 10-20 days | ฿23,460.00 |
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| 1.000 | 10-20 days | ฿78,000.00 |
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(2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
Used as a key intermediate in the synthesis of protease inhibitors, particularly in the development of antiviral drugs such as those targeting hepatitis C virus (HCV). Its stereochemistry and functional groups allow for selective binding to enzyme active sites, enhancing drug efficacy. The Boc-protected amine facilitates stepwise peptide coupling in solid-phase or solution-phase synthesis, while the carboxylic acid and hydrophobic biphenyl group contribute to molecular recognition and stability. Commonly employed in medicinal chemistry for constructing complex peptidomimetic structures with improved metabolic resistance and bioavailability.
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