(S)-Benzyl (2,6-dioxopiperidin-3-yl)carbamate
97%
- Product Code: 236018
CAS:
22785-43-9
| Molecular Weight: | 262.26 g./mol | Molecular Formula: | C₁₃H₁₄N₂O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09878852 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry, sealed |
Product Description:
Used as an intermediate in the synthesis of immunomodulatory drugs, particularly in the development of cereblon-targeting agents like lenalidomide derivatives. It plays a key role in constructing PROTACs (proteolysis-targeting chimeras), where it serves as a linker to bind cereblon E3 ubiquitin ligase, enabling targeted protein degradation. Its chiral structure is critical for biological activity, ensuring proper binding and selectivity in therapeutic applications for cancer and inflammatory diseases.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿2,340.00 |
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| 1.000 | 10-20 days | ฿5,990.00 |
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| 5.000 | 10-20 days | ฿22,020.00 |
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| 10.000 | 10-20 days | ฿38,290.00 |
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(S)-Benzyl (2,6-dioxopiperidin-3-yl)carbamate
Used as an intermediate in the synthesis of immunomodulatory drugs, particularly in the development of cereblon-targeting agents like lenalidomide derivatives. It plays a key role in constructing PROTACs (proteolysis-targeting chimeras), where it serves as a linker to bind cereblon E3 ubiquitin ligase, enabling targeted protein degradation. Its chiral structure is critical for biological activity, ensuring proper binding and selectivity in therapeutic applications for cancer and inflammatory diseases.
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