[S(R)]-N-[(S)-[(3-(Benzyloxy)-2-(dicyclohexylphosphino)phenyl)phenylmethyl]-2-methyl-2-propanesulfinamide
≥95%
- Product Code: 236124
CAS:
2565792-64-3
| Molecular Weight: | 589.82 g./mol | Molecular Formula: | C₃₆H₄₈NO₂PS |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, avoid light, inert gas storage |
Product Description:
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations, particularly in rhodium- or ruthenium-catalyzed asymmetric hydrogenation reactions. It is especially effective in the synthesis of chiral amines, amino acids, and other bioactive molecules where high enantiomeric excess is required. Due to its rigid, sterically demanding structure and well-defined stereochemistry, it helps achieve excellent stereocontrol in C–H activation and cross-coupling reactions. Its application extends to pharmaceutical intermediates synthesis, where precise chirality is critical for drug efficacy and safety. The sulfinamide and phosphine groups work in tandem to stabilize metal centers while directing asymmetric induction.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5mg | 10-20 days | ฿1,850.00 |
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| 25mg | 10-20 days | ฿6,820.00 |
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| 100mg | 10-20 days | ฿22,160.00 |
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[S(R)]-N-[(S)-[(3-(Benzyloxy)-2-(dicyclohexylphosphino)phenyl)phenylmethyl]-2-methyl-2-propanesulfinamide
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations, particularly in rhodium- or ruthenium-catalyzed asymmetric hydrogenation reactions. It is especially effective in the synthesis of chiral amines, amino acids, and other bioactive molecules where high enantiomeric excess is required. Due to its rigid, sterically demanding structure and well-defined stereochemistry, it helps achieve excellent stereocontrol in C–H activation and cross-coupling reactions. Its application extends to pharmaceutical intermediates synthesis, where precise chirality is critical for drug efficacy and safety. The sulfinamide and phosphine groups work in tandem to stabilize metal centers while directing asymmetric induction.
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