(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((4-methoxybenzyl)thio)propanoic acid
98%
- Product Code: 236419
CAS:
200354-43-4
| Molecular Weight: | 463.545 g./mol | Molecular Formula: | C₂₆H₂₅NO₅S |
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| Density: | Storage Condition: | 2-8°C, sealed, dry, inert gas |
Product Description:
Used primarily as a protected intermediate in solid-phase peptide synthesis, this compound enables the incorporation of cysteine derivatives with orthogonal protection. The Fmoc group allows for base-labile protection of the alpha-amine, compatible with repetitive deprotection cycles on automated synthesizers. The 4-methoxybenzyl thioether protects the thiol side chain, offering stability during chain assembly and selective removal under strong acid conditions, such as in TFA cleavage cocktails. Its structure supports the synthesis of complex peptides requiring cysteine residues with preserved reactivity for later disulfide bond formation. Commonly applied in the preparation of therapeutic peptides, enzyme substrates, and bioconjugates where precise thiol placement is critical.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿1,200.00 |
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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((4-methoxybenzyl)thio)propanoic acid
Used primarily as a protected intermediate in solid-phase peptide synthesis, this compound enables the incorporation of cysteine derivatives with orthogonal protection. The Fmoc group allows for base-labile protection of the alpha-amine, compatible with repetitive deprotection cycles on automated synthesizers. The 4-methoxybenzyl thioether protects the thiol side chain, offering stability during chain assembly and selective removal under strong acid conditions, such as in TFA cleavage cocktails. Its structure supports the synthesis of complex peptides requiring cysteine residues with preserved reactivity for later disulfide bond formation. Commonly applied in the preparation of therapeutic peptides, enzyme substrates, and bioconjugates where precise thiol placement is critical.
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