(S)-4-Isopropyl-3-(5, 5, 5-trifluoropentanoyl)oxazolidin-2-one
95%
- Product Code: 236543
CAS:
1401067-00-2
| Molecular Weight: | 267.24 g./mol | Molecular Formula: | C₁₁H₁₆F₃NO₃ |
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| EC Number: | MDL Number: | MFCD30829163 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, dry |
Product Description:
Used as a chiral auxiliary in asymmetric synthesis, this compound enables the selective formation of stereocenters in complex organic molecules. Its primary application is in the pharmaceutical industry, where it helps control stereochemistry during the synthesis of active pharmaceutical ingredients (APIs). The oxazolidinone ring acts as a temporary scaffold, directing the addition of reagents to one face of a molecule, leading to high enantiomeric excess. After serving its purpose, the auxiliary can be cleaved and often recycled. It is particularly effective in alkylations, aldol reactions, and Diels-Alder cycloadditions. Due to the electron-withdrawing trifluoropentanoyl group and the steric influence of the isopropyl substituent, it enhances both reactivity and selectivity. Commonly used in research and process chemistry for developing enantiopure drugs.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿2,130.00 |
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| 250mg | 10-20 days | ฿3,600.00 |
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| 1g | 10-20 days | ฿10,510.00 |
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| 5g | 10-20 days | ฿39,070.00 |
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(S)-4-Isopropyl-3-(5, 5, 5-trifluoropentanoyl)oxazolidin-2-one
Used as a chiral auxiliary in asymmetric synthesis, this compound enables the selective formation of stereocenters in complex organic molecules. Its primary application is in the pharmaceutical industry, where it helps control stereochemistry during the synthesis of active pharmaceutical ingredients (APIs). The oxazolidinone ring acts as a temporary scaffold, directing the addition of reagents to one face of a molecule, leading to high enantiomeric excess. After serving its purpose, the auxiliary can be cleaved and often recycled. It is particularly effective in alkylations, aldol reactions, and Diels-Alder cycloadditions. Due to the electron-withdrawing trifluoropentanoyl group and the steric influence of the isopropyl substituent, it enhances both reactivity and selectivity. Commonly used in research and process chemistry for developing enantiopure drugs.
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