(S)-1-(4-bromo-2-fluorophenyl)ethan-1-amine
95%
- Product Code: 236611
CAS:
1228559-00-9
| Molecular Weight: | 218.07 g./mol | Molecular Formula: | C₈H₉BrFN |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD07772674 | |
| Melting Point: | Boiling Point: | 250.1±25.0 °C(Predicted) | |
| Density: | 1.482±0.06 g/cm3(Predicted) | Storage Condition: | Room temperature, light-proof, inert gas |
Product Description:
Used as a chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where stereochemistry plays a critical role in biological activity. Its structure contains both bromo and fluoro substituents, making it valuable for further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Commonly employed in the preparation of neuroactive compounds and receptor modulators due to the aromatic halogen pattern influencing target binding affinity. The presence of the primary amine group allows for amide bond formation or reductive amination, enabling integration into larger molecular architectures. Frequently utilized in medicinal chemistry research for structure-activity relationship (SAR) studies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿12,400.00 |
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| 1.000 | 10-20 days | ฿50,060.00 |
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| 0.250 | 10-20 days | ฿18,540.00 |
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(S)-1-(4-bromo-2-fluorophenyl)ethan-1-amine
Used as a chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where stereochemistry plays a critical role in biological activity. Its structure contains both bromo and fluoro substituents, making it valuable for further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Commonly employed in the preparation of neuroactive compounds and receptor modulators due to the aromatic halogen pattern influencing target binding affinity. The presence of the primary amine group allows for amide bond formation or reductive amination, enabling integration into larger molecular architectures. Frequently utilized in medicinal chemistry research for structure-activity relationship (SAR) studies.
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