5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)pentanamide
98%
- Product Code: 236839
CAS:
2227450-68-0
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| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Used in pharmaceutical research as a key intermediate for synthesizing targeted protein degraders, especially in the development of PROTACs (Proteolysis Targeting Chimeras). Its structure enables linkage between an E3 ligase binder and a target protein ligand, facilitating intracellular protein degradation. The alkyne group allows for bioorthogonal conjugation via click chemistry, making it valuable in labeling, pull-down assays, and probe development. Also employed in medicinal chemistry for optimizing pharmacokinetic properties and improving cellular permeability in drug discovery programs.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿12,540.00 |
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| 250mg | 10-20 days | ฿16,990.00 |
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| 1g | 10-20 days | ฿54,820.00 |
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5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)pentanamide
Used in pharmaceutical research as a key intermediate for synthesizing targeted protein degraders, especially in the development of PROTACs (Proteolysis Targeting Chimeras). Its structure enables linkage between an E3 ligase binder and a target protein ligand, facilitating intracellular protein degradation. The alkyne group allows for bioorthogonal conjugation via click chemistry, making it valuable in labeling, pull-down assays, and probe development. Also employed in medicinal chemistry for optimizing pharmacokinetic properties and improving cellular permeability in drug discovery programs.
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