(2S,4R)-3-tert-Butyl 4-methyl 2-tert-butyloxazolidine-3,4-dicarboxylate

97%

  • Product Code: 236952
  CAS:    380429-42-5
Molecular Weight: Molecular Formula:
EC Number: MDL Number:
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Density: Storage Condition: 2-8°C, dry
Product Description: Used as a chiral auxiliary in asymmetric synthesis, enabling high stereoselectivity in carbon-carbon bond-forming reactions. It is particularly effective in enolate alkylations and aldol reactions, where it controls the formation of new stereocenters. The rigid oxazolidine ring and bulky tert-butyl groups shield one face of the molecule, directing reagent approach to the opposite face. After the desired transformation, the auxiliary can be cleaved under mild conditions to yield enantiomerically enriched carboxylic acids, alcohols, or other functionalized products. Widely employed in the synthesis of complex natural products and pharmaceutical intermediates.
Sizes / Availability / Pricing:
Size Availability Price Quantity
250mg 10-20 days ฿4,480.00
+
-
1g 10-20 days ฿11,590.00
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-
5g 10-20 days ฿35,920.00
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-
(2S,4R)-3-tert-Butyl 4-methyl 2-tert-butyloxazolidine-3,4-dicarboxylate
Used as a chiral auxiliary in asymmetric synthesis, enabling high stereoselectivity in carbon-carbon bond-forming reactions. It is particularly effective in enolate alkylations and aldol reactions, where it controls the formation of new stereocenters. The rigid oxazolidine ring and bulky tert-butyl groups shield one face of the molecule, directing reagent approach to the opposite face. After the desired transformation, the auxiliary can be cleaved under mild conditions to yield enantiomerically enriched carboxylic acids, alcohols, or other functionalized products. Widely employed in the synthesis of complex natural products and pharmaceutical intermediates.
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