(S,R,S)-AHPC-PEG₆-Azide
98%
- Product Code: 237116
CAS:
2086298-71-5
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in PROTAC (Proteolysis Targeting Chimeras) technology to facilitate targeted protein degradation. Acts as a linker with an azide functional group that enables click chemistry for conjugation to complementary moieties, such as alkyne-bearing ligands. The PEG6 spacer enhances solubility and provides optimal distance between the target-binding and E3 ligase-binding components of the PROTAC molecule. Its stereochemistry supports improved binding selectivity and stability, contributing to efficient formation of the ternary complex required for ubiquitination and subsequent degradation of disease-related proteins. Commonly applied in drug discovery and development for cancer, neurodegenerative diseases, and other conditions involving undruggable targets.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿19,460.00 |
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| 250mg | 10-20 days | ฿39,890.00 |
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(S,R,S)-AHPC-PEG₆-Azide
Used in PROTAC (Proteolysis Targeting Chimeras) technology to facilitate targeted protein degradation. Acts as a linker with an azide functional group that enables click chemistry for conjugation to complementary moieties, such as alkyne-bearing ligands. The PEG6 spacer enhances solubility and provides optimal distance between the target-binding and E3 ligase-binding components of the PROTAC molecule. Its stereochemistry supports improved binding selectivity and stability, contributing to efficient formation of the ternary complex required for ubiquitination and subsequent degradation of disease-related proteins. Commonly applied in drug discovery and development for cancer, neurodegenerative diseases, and other conditions involving undruggable targets.
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