(2S,4S)-1-[(tert-butoxy)carbonyl]-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid

97%

  • Product Code: 237321
  CAS:    470482-41-8
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Density: Storage Condition: Room temperature
Product Description: Widely used in pharmaceutical synthesis, this compound serves as a chiral building block for the preparation of biologically active molecules. Its rigid pyrrolidine backbone and trifluoromethyl group enhance metabolic stability and binding selectivity in drug candidates. It is particularly valuable in the development of protease inhibitors and other enzyme-targeted therapies. The Boc-protected amine allows for straightforward deprotection and coupling in peptide-like synthesis, making it suitable for use in solid-phase and solution-phase applications. Its stereochemistry enables precise control over 3D structure, which is critical in optimizing potency and reducing off-target effects in medicinal chemistry programs.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days $102.13
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250mg 10-20 days $206.66
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1g 10-20 days $824.25
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-
5g 10-20 days $3,583.06
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(2S,4S)-1-[(tert-butoxy)carbonyl]-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid
Widely used in pharmaceutical synthesis, this compound serves as a chiral building block for the preparation of biologically active molecules. Its rigid pyrrolidine backbone and trifluoromethyl group enhance metabolic stability and binding selectivity in drug candidates. It is particularly valuable in the development of protease inhibitors and other enzyme-targeted therapies. The Boc-protected amine allows for straightforward deprotection and coupling in peptide-like synthesis, making it suitable for use in solid-phase and solution-phase applications. Its stereochemistry enables precise control over 3D structure, which is critical in optimizing potency and reducing off-target effects in medicinal chemistry programs.
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