(2S,5S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5-methylpyrrolidine-2-carboxylicacid
97%
- Product Code: 237659
CAS:
1932784-54-7
| Molecular Weight: | 351.40 g./mol | Molecular Formula: | C₂₁H₂₁NO₄ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a chiral building block in the synthesis of peptide-based pharmaceuticals and bioactive molecules. Its stereochemistry makes it valuable in asymmetric synthesis, particularly in the development of protease inhibitors and other therapeutic agents requiring high enantiomeric purity. Commonly employed in solid-phase peptide synthesis (SPPS) as a protected amino acid derivative, facilitating the construction of complex peptides with controlled conformation. The fluorenylmethyloxycarbonyl (Fmoc) group allows for mild base-labile protection, enabling selective deprotection in multi-step syntheses. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to its constrained pyrrolidine scaffold, which can influence peptide backbone conformation and metabolic stability.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿6,870.00 |
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| 250mg | 10-20 days | ฿11,670.00 |
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| 1g | 10-20 days | ฿31,460.00 |
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(2S,5S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5-methylpyrrolidine-2-carboxylicacid
Used as a chiral building block in the synthesis of peptide-based pharmaceuticals and bioactive molecules. Its stereochemistry makes it valuable in asymmetric synthesis, particularly in the development of protease inhibitors and other therapeutic agents requiring high enantiomeric purity. Commonly employed in solid-phase peptide synthesis (SPPS) as a protected amino acid derivative, facilitating the construction of complex peptides with controlled conformation. The fluorenylmethyloxycarbonyl (Fmoc) group allows for mild base-labile protection, enabling selective deprotection in multi-step syntheses. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to its constrained pyrrolidine scaffold, which can influence peptide backbone conformation and metabolic stability.
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