(S)-2-(bis(3,5-dimethylphenyl)((trimethylsilyl)oxy)methyl)pyrrolidine
97%
- Product Code: 237687
CAS:
848821-60-3
| Molecular Weight: | 381.63 g./mol | Molecular Formula: | C₂₄H₃₅NOSi |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD14636497 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, light-proof, inert gas |
Product Description:
Used as a chiral auxiliary in asymmetric synthesis, particularly in enantioselective organocatalysis. It helps control stereochemistry in carbon-carbon bond-forming reactions, such as aldol or Mannich-type reactions, by directing the approach of reagents through steric and electronic effects. The silyloxy group enhances stability and modulates reactivity, while the pyrrolidine core acts as an organocatalyst scaffold. Commonly employed in the synthesis of complex natural products and pharmaceuticals where high enantiomeric excess is required. Its bulky aryl groups provide excellent stereoselectivity, making it valuable in advanced intermediate synthesis.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿2,950.00 |
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| 1g | 10-20 days | ฿19,040.00 |
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| 250mg | 10-20 days | ฿5,830.00 |
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(S)-2-(bis(3,5-dimethylphenyl)((trimethylsilyl)oxy)methyl)pyrrolidine
Used as a chiral auxiliary in asymmetric synthesis, particularly in enantioselective organocatalysis. It helps control stereochemistry in carbon-carbon bond-forming reactions, such as aldol or Mannich-type reactions, by directing the approach of reagents through steric and electronic effects. The silyloxy group enhances stability and modulates reactivity, while the pyrrolidine core acts as an organocatalyst scaffold. Commonly employed in the synthesis of complex natural products and pharmaceuticals where high enantiomeric excess is required. Its bulky aryl groups provide excellent stereoselectivity, making it valuable in advanced intermediate synthesis.
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