(S)-2-(4-Methoxy-6-methylpyridin-2-yl)-4-phenyl-4,5-dihydrooxazole

98%

  • Product Code: 237856
  CAS:    2757082-39-4
Molecular Weight: 268.315 g./mol Molecular Formula: C₁₆H₁₆N₂O₂
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, light-proof, inert gas
Product Description: Used as a key chiral intermediate in the synthesis of proton pump inhibitors (PPIs), particularly in the production of esomeprazole and related anti-ulcer drugs. Its stereochemistry enables selective inhibition of the gastric acid pump in the stomach lining, improving efficacy and reducing side effects compared to racemic mixtures. The compound’s oxazole ring enhances metabolic stability and bioavailability, making it valuable in developing long-acting gastrointestinal medications. It is also employed in asymmetric synthesis for constructing complex heterocyclic systems in pharmaceutical research.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days $416.91
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250mg 10-20 days $704.96
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-
1g 10-20 days $2,375.41
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(S)-2-(4-Methoxy-6-methylpyridin-2-yl)-4-phenyl-4,5-dihydrooxazole
Used as a key chiral intermediate in the synthesis of proton pump inhibitors (PPIs), particularly in the production of esomeprazole and related anti-ulcer drugs. Its stereochemistry enables selective inhibition of the gastric acid pump in the stomach lining, improving efficacy and reducing side effects compared to racemic mixtures. The compound’s oxazole ring enhances metabolic stability and bioavailability, making it valuable in developing long-acting gastrointestinal medications. It is also employed in asymmetric synthesis for constructing complex heterocyclic systems in pharmaceutical research.
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