(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-dimethylphenyl)propanoic acid

95%

  • Product Code: 237921
  CAS:    1270295-08-3
Molecular Weight: 415.48 g./mol Molecular Formula: C₂₆H₂₅NO₄
EC Number: MDL Number: MFCD09842054
Melting Point: Boiling Point: 642.6±55.0 °C(Predicted)
Density: 1.236±0.06 g/cm3(Predicted) Storage Condition: 2-8°C, sealed, dry
Product Description: Used as a key intermediate in peptide synthesis, particularly in the preparation of structurally complex peptides and peptidomimetics. Its primary application lies in solid-phase peptide synthesis (SPPS), where the Fmoc group provides temporary Nα-amino protection that is easily removed under mild basic conditions, allowing stepwise assembly of peptide chains. The chiral (S)-configuration ensures stereochemical control during coupling, which is critical for achieving desired biological activity in the final peptide product. The 2,3-dimethylphenyl side chain imparts steric and hydrophobic characteristics, making it useful in the design of enzyme inhibitors or receptor ligands where side chain bulk influences binding affinity and selectivity. Commonly employed in pharmaceutical research and development for synthesizing bioactive molecules and optimizing peptide drug candidates.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days ฿3,340.00
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0.250 10-20 days ฿6,260.00
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1.000 10-20 days ฿19,610.00
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5.000 10-20 days ฿68,630.00
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(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-dimethylphenyl)propanoic acid
Used as a key intermediate in peptide synthesis, particularly in the preparation of structurally complex peptides and peptidomimetics. Its primary application lies in solid-phase peptide synthesis (SPPS), where the Fmoc group provides temporary Nα-amino protection that is easily removed under mild basic conditions, allowing stepwise assembly of peptide chains. The chiral (S)-configuration ensures stereochemical control during coupling, which is critical for achieving desired biological activity in the final peptide product. The 2,3-dimethylphenyl side chain imparts steric and hydrophobic characteristics, making it useful in the design of enzyme inhibitors or receptor ligands where side chain bulk influences binding affinity and selectivity. Commonly employed in pharmaceutical research and development for synthesizing bioactive molecules and optimizing peptide drug candidates.
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