2-(4,7,10-Tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid

98%

  • Product Code: 238259
  CAS:    247193-74-4
Molecular Weight: 530.65 g./mol Molecular Formula: C₂₅H₄₆N₄O₈
EC Number: MDL Number: MFCD11226800
Melting Point: 138 °C Boiling Point: 611.6±55.0 °C(Predicted)
Density: 1.126±0.06 g/cm3(Predicted) Storage Condition: 2-8°C, sealed, dry
Product Description: Used primarily in the synthesis of MRI contrast agents, this compound serves as a key chelating agent for binding gadolinium(III) and other metal ions. Its macrocyclic structure provides high stability and selectivity, reducing the risk of metal ion release in biological systems. It is especially valuable in developing targeted imaging agents due to the presence of a reactive acetic acid side chain, which can be easily conjugated to biomolecules such as peptides or antibodies. The tert-butoxycarbonyl (Boc) groups act as protecting groups, allowing for controlled deprotection and further functionalization during multi-step syntheses. Commonly employed in radiopharmaceutical and diagnostic research, it enables the creation of safer, more effective imaging probes.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days $468.49
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-
1g 10-20 days $2,148.53
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2-(4,7,10-Tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid
Used primarily in the synthesis of MRI contrast agents, this compound serves as a key chelating agent for binding gadolinium(III) and other metal ions. Its macrocyclic structure provides high stability and selectivity, reducing the risk of metal ion release in biological systems. It is especially valuable in developing targeted imaging agents due to the presence of a reactive acetic acid side chain, which can be easily conjugated to biomolecules such as peptides or antibodies. The tert-butoxycarbonyl (Boc) groups act as protecting groups, allowing for controlled deprotection and further functionalization during multi-step syntheses. Commonly employed in radiopharmaceutical and diagnostic research, it enables the creation of safer, more effective imaging probes.
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