5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)-1H-indole

98%

  • Product Code: 238301
  CAS:    837392-61-7
Molecular Weight: 311.107 g./mol Molecular Formula: C₁₅H₁₇BF₃NO₂
EC Number: MDL Number: MFCD20226769
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, Inert Gas
Product Description: Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing complex indole derivatives. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity in drug candidates, which is beneficial in the development of bioactive molecules. It is particularly useful in the preparation of kinase inhibitors and CNS-active compounds. Additionally, it finds application in materials science for building conjugated systems in organic electronics.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days Ft69,811.01
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-
250mg 10-20 days Ft118,535.42
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-
1g 10-20 days Ft391,330.65
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-
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)-1H-indole
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing complex indole derivatives. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity in drug candidates, which is beneficial in the development of bioactive molecules. It is particularly useful in the preparation of kinase inhibitors and CNS-active compounds. Additionally, it finds application in materials science for building conjugated systems in organic electronics.
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