8-(Trifluoromethyl)quinoline-5-carbonitrile
95%
- Product Code: 238400
CAS:
2922283-53-0
| Molecular Weight: | 222.17 g./mol | Molecular Formula: | C₁₁H₅F₃N₂ |
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| Density: | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals to improve metabolic stability and bioavailability. The electron-withdrawing trifluoromethyl and nitrile groups contribute to enhanced lipophilicity and resistance to degradation, making it valuable in designing bioactive molecules. Additionally, it serves as a building block in materials science for creating fluorescent probes and optoelectronic materials due to its rigid aromatic framework and electronic properties.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿32,250.00 |
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| 1.000 | 10-20 days | ฿147,910.00 |
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| 0.250 | 10-20 days | ฿54,790.00 |
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8-(Trifluoromethyl)quinoline-5-carbonitrile
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals to improve metabolic stability and bioavailability. The electron-withdrawing trifluoromethyl and nitrile groups contribute to enhanced lipophilicity and resistance to degradation, making it valuable in designing bioactive molecules. Additionally, it serves as a building block in materials science for creating fluorescent probes and optoelectronic materials due to its rigid aromatic framework and electronic properties.
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