2-[4,7,10-tris(carboxymethyl)-6-[(4-isothiocyanatophenyl)methyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
98%
- Product Code: 238502
CAS:
127985-74-4
| Molecular Weight: | 551.6 g./mol | Molecular Formula: | C₂₄H₃₃N₅O₈S |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used primarily as a bifunctional chelating agent in radiopharmaceuticals, this compound enables stable conjugation of radioactive metal ions to targeting biomolecules such as antibodies or peptides. Its isothiocyanate group reacts selectively with amine groups on proteins, forming stable thiourea linkages, while the macrocyclic structure strongly binds diagnostic or therapeutic radionuclides like gallium-68, copper-64, or yttrium-90. This makes it valuable in nuclear medicine for PET imaging and targeted radiotherapy, especially in cancer diagnostics and treatment. The compound’s design supports high in vivo stability and efficient labeling under mild conditions, improving pharmacokinetics and reducing off-target accumulation of radioactivity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5mg | 10-20 days | $864.24 |
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| 25mg | 10-20 days | $2,592.72 |
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2-[4,7,10-tris(carboxymethyl)-6-[(4-isothiocyanatophenyl)methyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
Used primarily as a bifunctional chelating agent in radiopharmaceuticals, this compound enables stable conjugation of radioactive metal ions to targeting biomolecules such as antibodies or peptides. Its isothiocyanate group reacts selectively with amine groups on proteins, forming stable thiourea linkages, while the macrocyclic structure strongly binds diagnostic or therapeutic radionuclides like gallium-68, copper-64, or yttrium-90. This makes it valuable in nuclear medicine for PET imaging and targeted radiotherapy, especially in cancer diagnostics and treatment. The compound’s design supports high in vivo stability and efficient labeling under mild conditions, improving pharmacokinetics and reducing off-target accumulation of radioactivity.
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