2',4-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]-pyridin-3-yl]-[1,1'-biphenyl]-2-carbonitrile
≥98%(HPLC)
- Product Code: 238942
CAS:
628690-75-5
| Molecular Weight: | 407.39 g./mol | Molecular Formula: | C₂₃H₁₆F₃N₃O |
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| Density: | 1.31 g/cm3 | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of pharmaceutical agents for treating autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. Its structure enables selective modulation of JAK enzyme activity, contributing to reduced inflammation and immune system regulation. Due to its fluorinated and heterocyclic components, it exhibits enhanced metabolic stability and binding affinity, making it a valuable intermediate in medicinal chemistry for optimizing drug potency and pharmacokinetic properties.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 10mg | 10-20 days | ฿24,740.00 |
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2',4-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]-pyridin-3-yl]-[1,1'-biphenyl]-2-carbonitrile
Used in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of pharmaceutical agents for treating autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. Its structure enables selective modulation of JAK enzyme activity, contributing to reduced inflammation and immune system regulation. Due to its fluorinated and heterocyclic components, it exhibits enhanced metabolic stability and binding affinity, making it a valuable intermediate in medicinal chemistry for optimizing drug potency and pharmacokinetic properties.
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