TCO-pnb ester

95%

  • Product Code: 238956
  CAS:    2389122-16-9
Molecular Weight: 291.3 g./mol Molecular Formula: C₁₅H₁₇NO₅
EC Number: MDL Number: MFCD29052196
Melting Point: Boiling Point: 433.9±45.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted) Storage Condition: -20°C, Sealed, Inert Gas
Product Description: Used in bioorthogonal chemistry for rapid and specific labeling of biomolecules in live cells. Enables targeted release of payloads such as drugs or imaging agents through trans-cyclooctene-mediated cleavage. Commonly applied in antibody-drug conjugates (ADCs) and targeted therapy to improve selectivity and reduce off-target effects. Also utilized in pretargeted imaging strategies, where it facilitates high-contrast visualization in vivo by decoupling targeting and signal delivery steps. Its fast reaction kinetics with tetrazine allows efficient conjugation under physiological conditions without interfering with native biochemical processes.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days $528.49
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250mg 10-20 days $993.00
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TCO-pnb ester
Used in bioorthogonal chemistry for rapid and specific labeling of biomolecules in live cells. Enables targeted release of payloads such as drugs or imaging agents through trans-cyclooctene-mediated cleavage. Commonly applied in antibody-drug conjugates (ADCs) and targeted therapy to improve selectivity and reduce off-target effects. Also utilized in pretargeted imaging strategies, where it facilitates high-contrast visualization in vivo by decoupling targeting and signal delivery steps. Its fast reaction kinetics with tetrazine allows efficient conjugation under physiological conditions without interfering with native biochemical processes.
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