TCO-pnb ester
95%
- Product Code: 238956
CAS:
2389122-16-9
Molecular Weight: | 291.3 g./mol | Molecular Formula: | C₁₅H₁₇NO₅ |
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EC Number: | MDL Number: | MFCD29052196 | |
Melting Point: | Boiling Point: | 433.9±45.0 °C(Predicted) | |
Density: | 1.24±0.1 g/cm3(Predicted) | Storage Condition: | -20°C, Sealed, Inert Gas |
Product Description:
Used in bioorthogonal chemistry for rapid and specific labeling of biomolecules in live cells. Enables targeted release of payloads such as drugs or imaging agents through trans-cyclooctene-mediated cleavage. Commonly applied in antibody-drug conjugates (ADCs) and targeted therapy to improve selectivity and reduce off-target effects. Also utilized in pretargeted imaging strategies, where it facilitates high-contrast visualization in vivo by decoupling targeting and signal delivery steps. Its fast reaction kinetics with tetrazine allows efficient conjugation under physiological conditions without interfering with native biochemical processes.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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100mg | 10-20 days | $528.49 |
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250mg | 10-20 days | $993.00 |
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TCO-pnb ester
Used in bioorthogonal chemistry for rapid and specific labeling of biomolecules in live cells. Enables targeted release of payloads such as drugs or imaging agents through trans-cyclooctene-mediated cleavage. Commonly applied in antibody-drug conjugates (ADCs) and targeted therapy to improve selectivity and reduce off-target effects. Also utilized in pretargeted imaging strategies, where it facilitates high-contrast visualization in vivo by decoupling targeting and signal delivery steps. Its fast reaction kinetics with tetrazine allows efficient conjugation under physiological conditions without interfering with native biochemical processes.
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