2-(2,3,5,6-tetrafluoro-4-iodo-phenyl)-[1,3]dioxolane
98%
- Product Code: 239030
CAS:
837368-27-1
| Molecular Weight: | 348.04 g./mol | Molecular Formula: | C₉H₅F₄IO₂ |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | 2-8 °C, sealed, dry |
Product Description:
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its unique halogen and protecting group arrangement. The iodine moiety allows for further functionalization via cross-coupling reactions such as Suzuki or Heck couplings, enabling the construction of complex fluorinated aromatic systems. The dioxolane group acts as a protected form of a carbonyl, which can be deprotected under mild acidic conditions to release the corresponding ketone or aldehyde, making it valuable in multi-step organic syntheses. Its high fluorine content enhances lipophilicity and metabolic stability in bioactive molecules, often improving cell membrane permeability in drug candidates. Commonly employed in the development of specialty materials and active ingredients in crop protection agents.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 250mg | 10-20 days | $387.90 |
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| bulk | 10-20 days | $0.00 |
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| 1g | 10-20 days | $1,131.36 |
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2-(2,3,5,6-tetrafluoro-4-iodo-phenyl)-[1,3]dioxolane
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its unique halogen and protecting group arrangement. The iodine moiety allows for further functionalization via cross-coupling reactions such as Suzuki or Heck couplings, enabling the construction of complex fluorinated aromatic systems. The dioxolane group acts as a protected form of a carbonyl, which can be deprotected under mild acidic conditions to release the corresponding ketone or aldehyde, making it valuable in multi-step organic syntheses. Its high fluorine content enhances lipophilicity and metabolic stability in bioactive molecules, often improving cell membrane permeability in drug candidates. Commonly employed in the development of specialty materials and active ingredients in crop protection agents.
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