TRPM4-IN-1
10mM in DMSO
- Product Code: 239156
CAS:
351424-20-9
| Molecular Weight: | 340.16 g./mol | Molecular Formula: | C₁₅H₁₁Cl₂NO₄ |
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| Density: | Storage Condition: | -20°C |
Product Description:
TRPM4-IN-1 is a potent and selective inhibitor of the TRPM4 ion channel, which plays a role in regulating calcium-dependent cellular processes. It is primarily used in research settings to study the physiological and pathological roles of TRPM4 in various diseases.
One key application is in cardiovascular research, where TRPM4-IN-1 helps investigate conditions such as ischemia-reperfusion injury and arrhythmias. By blocking TRPM4 activity, it reduces abnormal electrical activity in the heart, suggesting potential therapeutic pathways for cardiac protection.
In neuroscience, TRPM4-IN-1 is used to explore neuronal excitability and cell death mechanisms following stroke or brain injury. Inhibiting TRPM4 with this compound has been shown to reduce cerebral damage in preclinical models, highlighting its relevance in neuroprotection studies.
It is also applied in immunology and cancer research, as TRPM4 is involved in T-cell activation and cancer cell migration. TRPM4-IN-1 enables scientists to probe how ion channel modulation affects immune responses and tumor progression.
Overall, TRPM4-IN-1 serves as a valuable pharmacological tool for understanding disease mechanisms and identifying potential targets for drug development.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿3,790.00 |
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TRPM4-IN-1
TRPM4-IN-1 is a potent and selective inhibitor of the TRPM4 ion channel, which plays a role in regulating calcium-dependent cellular processes. It is primarily used in research settings to study the physiological and pathological roles of TRPM4 in various diseases.
One key application is in cardiovascular research, where TRPM4-IN-1 helps investigate conditions such as ischemia-reperfusion injury and arrhythmias. By blocking TRPM4 activity, it reduces abnormal electrical activity in the heart, suggesting potential therapeutic pathways for cardiac protection.
In neuroscience, TRPM4-IN-1 is used to explore neuronal excitability and cell death mechanisms following stroke or brain injury. Inhibiting TRPM4 with this compound has been shown to reduce cerebral damage in preclinical models, highlighting its relevance in neuroprotection studies.
It is also applied in immunology and cancer research, as TRPM4 is involved in T-cell activation and cancer cell migration. TRPM4-IN-1 enables scientists to probe how ion channel modulation affects immune responses and tumor progression.
Overall, TRPM4-IN-1 serves as a valuable pharmacological tool for understanding disease mechanisms and identifying potential targets for drug development.
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