TIC10
10mM in DMSO
- Product Code: 239289
CAS:
1616632-77-9
Molecular Weight: | 386.49 g./mol | Molecular Formula: | C₂₄H₂₆N₄O |
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EC Number: | MDL Number: | MFCD28118993 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | -20°C |
Product Description:
TIC10 is primarily investigated for its potential in cancer therapy due to its ability to activate the tumor suppressor protein TRAIL (TNF-related apoptosis-inducing ligand). It promotes apoptosis in cancer cells by upregulating TRAIL receptors, making tumor cells more susceptible to immune-mediated destruction. TIC10 has shown activity across various cancer types, including glioblastoma, breast, and colon cancers, especially in models resistant to conventional treatments. Its ability to cross the blood-brain barrier enhances its utility in treating brain tumors. Research also explores its role in combination therapies to improve treatment efficacy and overcome drug resistance.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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1ml | 10-20 days | ฿1,850.00 |
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TIC10
TIC10 is primarily investigated for its potential in cancer therapy due to its ability to activate the tumor suppressor protein TRAIL (TNF-related apoptosis-inducing ligand). It promotes apoptosis in cancer cells by upregulating TRAIL receptors, making tumor cells more susceptible to immune-mediated destruction. TIC10 has shown activity across various cancer types, including glioblastoma, breast, and colon cancers, especially in models resistant to conventional treatments. Its ability to cross the blood-brain barrier enhances its utility in treating brain tumors. Research also explores its role in combination therapies to improve treatment efficacy and overcome drug resistance.
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