TM-5441
10mM in DMSO
- Product Code: 239300
CAS:
1190221-43-2
Molecular Weight: | 428.82 g./mol | Molecular Formula: | C₂₁H₁₇ClN₂O₆ |
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Density: | Storage Condition: | -20°C |
Product Description:
TM-5441 is a selective inhibitor of plasminogen activator inhibitor-1 (PAI-1). It is primarily used in research settings to study fibrotic diseases, thrombosis, and metabolic disorders. By inhibiting PAI-1, TM-5441 helps reduce extracellular matrix accumulation, making it a candidate for investigating conditions such as liver fibrosis, kidney fibrosis, and pulmonary fibrosis. It has also shown potential in improving insulin sensitivity and glucose metabolism in preclinical models of type 2 diabetes. Additionally, TM-5441 is used to explore the role of PAI-1 in cancer progression, as elevated PAI-1 levels are associated with tumor invasion and poor prognosis. Its application remains experimental and is not approved for clinical use.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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1ml | 10-20 days | ฿7,910.00 |
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TM-5441
TM-5441 is a selective inhibitor of plasminogen activator inhibitor-1 (PAI-1). It is primarily used in research settings to study fibrotic diseases, thrombosis, and metabolic disorders. By inhibiting PAI-1, TM-5441 helps reduce extracellular matrix accumulation, making it a candidate for investigating conditions such as liver fibrosis, kidney fibrosis, and pulmonary fibrosis. It has also shown potential in improving insulin sensitivity and glucose metabolism in preclinical models of type 2 diabetes. Additionally, TM-5441 is used to explore the role of PAI-1 in cancer progression, as elevated PAI-1 levels are associated with tumor invasion and poor prognosis. Its application remains experimental and is not approved for clinical use.
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