T0070907
10mM in DMSO
- Product Code: 239319
CAS:
313516-66-4
| Molecular Weight: | 277.66 g./mol | Molecular Formula: | C₁₂H₈ClN₃O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00121849 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
T0070907 is a potent and selective antagonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It is widely used in research settings to investigate the role of PPARγ in various biological processes, particularly in adipogenesis, insulin sensitivity, and inflammation. By inhibiting PPARγ activity, T0070907 effectively blocks the differentiation of preadipocytes into mature adipocytes, making it a valuable tool in studies related to obesity and fat cell development.
In metabolic research, T0070907 helps dissect the mechanisms of insulin signaling and glucose homeostasis, as PPARγ is a key regulator of these pathways. It is also employed in cancer research, where PPARγ modulation has been linked to tumor growth and cell proliferation, especially in liposarcomas and other malignancies. Additionally, due to its anti-adipogenic properties, it is used to study the reversibility of insulin resistance and the impact of fat accumulation on metabolic health.
Its high selectivity and cell permeability make T0070907 suitable for in vitro and in vivo experimental models, supporting pharmacological and molecular studies aimed at understanding and targeting metabolic diseases, diabetes, and certain cancers.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿3,540.00 |
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T0070907
T0070907 is a potent and selective antagonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It is widely used in research settings to investigate the role of PPARγ in various biological processes, particularly in adipogenesis, insulin sensitivity, and inflammation. By inhibiting PPARγ activity, T0070907 effectively blocks the differentiation of preadipocytes into mature adipocytes, making it a valuable tool in studies related to obesity and fat cell development.
In metabolic research, T0070907 helps dissect the mechanisms of insulin signaling and glucose homeostasis, as PPARγ is a key regulator of these pathways. It is also employed in cancer research, where PPARγ modulation has been linked to tumor growth and cell proliferation, especially in liposarcomas and other malignancies. Additionally, due to its anti-adipogenic properties, it is used to study the reversibility of insulin resistance and the impact of fat accumulation on metabolic health.
Its high selectivity and cell permeability make T0070907 suitable for in vitro and in vivo experimental models, supporting pharmacological and molecular studies aimed at understanding and targeting metabolic diseases, diabetes, and certain cancers.
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