1-(p-Toluenesulfonyl)imidazole
99%
- Product Code: 239726
Alias:
1-P-methylbenzenesulfonylimidazole; 1-P-toluenesulfonyl-1H-imidazole
CAS:
2232-08-8
Molecular Weight: | 222.26 g./mol | Molecular Formula: | C₁₀H₁₀N₂O₂S |
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EC Number: | 218-771-9 | MDL Number: | MFCD00005285 |
Melting Point: | 76-78 °C(lit.) | Boiling Point: | |
Density: | Storage Condition: | Room temperature |
Product Description:
Used as a versatile sulfonating agent in organic synthesis, particularly for the introduction of the p-toluenesulfonyl (tosyl) group to alcohols, amines, and other nucleophiles. It is effective in converting alcohols to tosylates, which are good leaving groups used in substitution and elimination reactions. Preferred over traditional reagents like p-toluenesulfonyl chloride due to its higher selectivity and milder reaction conditions, especially in peptide and carbohydrate chemistry. Also employed in the protection of functional groups and in the activation of hydroxyl groups for nucleophilic displacement without racemization in chiral molecules. Its stability and ease of handling make it suitable for use in both laboratory-scale and industrial applications.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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5g | 10-20 days | ฿180.00 |
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25g | 10-20 days | ฿660.00 |
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100g | 10-20 days | ฿2,300.00 |
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500g | 10-20 days | ฿11,200.00 |
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1-(p-Toluenesulfonyl)imidazole
Used as a versatile sulfonating agent in organic synthesis, particularly for the introduction of the p-toluenesulfonyl (tosyl) group to alcohols, amines, and other nucleophiles. It is effective in converting alcohols to tosylates, which are good leaving groups used in substitution and elimination reactions. Preferred over traditional reagents like p-toluenesulfonyl chloride due to its higher selectivity and milder reaction conditions, especially in peptide and carbohydrate chemistry. Also employed in the protection of functional groups and in the activation of hydroxyl groups for nucleophilic displacement without racemization in chiral molecules. Its stability and ease of handling make it suitable for use in both laboratory-scale and industrial applications.
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