1-(p-Toluenesulfonyl)imidazole

99%

  • Product Code: 239726
  Alias:    1-P-methylbenzenesulfonylimidazole; 1-P-toluenesulfonyl-1H-imidazole
  CAS:    2232-08-8
Molecular Weight: 222.26 g./mol Molecular Formula: C₁₀H₁₀N₂O₂S
EC Number: 218-771-9 MDL Number: MFCD00005285
Melting Point: 76-78 °C(lit.) Boiling Point:
Density: Storage Condition: Room temperature
Product Description: Used as a versatile sulfonating agent in organic synthesis, particularly for the introduction of the p-toluenesulfonyl (tosyl) group to alcohols, amines, and other nucleophiles. It is effective in converting alcohols to tosylates, which are good leaving groups used in substitution and elimination reactions. Preferred over traditional reagents like p-toluenesulfonyl chloride due to its higher selectivity and milder reaction conditions, especially in peptide and carbohydrate chemistry. Also employed in the protection of functional groups and in the activation of hydroxyl groups for nucleophilic displacement without racemization in chiral molecules. Its stability and ease of handling make it suitable for use in both laboratory-scale and industrial applications.
Sizes / Availability / Pricing:
Size Availability Price Quantity
5g 10-20 days ฿180.00
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25g 10-20 days ฿660.00
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100g 10-20 days ฿2,300.00
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500g 10-20 days ฿11,200.00
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1-(p-Toluenesulfonyl)imidazole
Used as a versatile sulfonating agent in organic synthesis, particularly for the introduction of the p-toluenesulfonyl (tosyl) group to alcohols, amines, and other nucleophiles. It is effective in converting alcohols to tosylates, which are good leaving groups used in substitution and elimination reactions. Preferred over traditional reagents like p-toluenesulfonyl chloride due to its higher selectivity and milder reaction conditions, especially in peptide and carbohydrate chemistry. Also employed in the protection of functional groups and in the activation of hydroxyl groups for nucleophilic displacement without racemization in chiral molecules. Its stability and ease of handling make it suitable for use in both laboratory-scale and industrial applications.
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