4-(trifluoromethyl)thiazol-2-amine
95%
- Product Code: 240267
Alias:
2-amino-4-trifluoromethyl-1,3-thiazole; 4-trifluoromethyl-thiazole-2-amine; 4-(TRIFLUOROMETHYL)-1,3-THIAZOL-2-AMINE
CAS:
349-49-5
Molecular Weight: | 168.14 g./mol | Molecular Formula: | C₄H₃F₃N₂S |
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EC Number: | MDL Number: | MFCD00832759 | |
Melting Point: | 60-62℃ | Boiling Point: | 214℃ at 760 mmHg |
Density: | 1.557±0.06 g/ml(Predicted) | Storage Condition: | Room temperature, sealed, dry |
Product Description:
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antifungal and anticancer agents. Its structure supports the design of kinase inhibitors and bioactive molecules due to the electron-withdrawing trifluoromethyl group enhancing metabolic stability and membrane permeability. Also employed in agrochemicals for creating herbicides and pesticides, where the thiazole ring contributes to improved biological activity and selectivity. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidates.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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1.000 | 10-20 days | Ft3,005.37 |
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5.000 | 10-20 days | Ft24,589.35 |
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4-(trifluoromethyl)thiazol-2-amine
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antifungal and anticancer agents. Its structure supports the design of kinase inhibitors and bioactive molecules due to the electron-withdrawing trifluoromethyl group enhancing metabolic stability and membrane permeability. Also employed in agrochemicals for creating herbicides and pesticides, where the thiazole ring contributes to improved biological activity and selectivity. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidates.
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