4-(trifluoromethyl)thiazol-2-amine

95%

  • Product Code: 240267
  Alias:    2-amino-4-trifluoromethyl-1,3-thiazole; 4-trifluoromethyl-thiazole-2-amine; 4-(TRIFLUOROMETHYL)-1,3-THIAZOL-2-AMINE
  CAS:    349-49-5
Molecular Weight: 168.14 g./mol Molecular Formula: C₄H₃F₃N₂S
EC Number: MDL Number: MFCD00832759
Melting Point: 60-62℃ Boiling Point: 214℃ at 760 mmHg
Density: 1.557±0.06 g/ml(Predicted) Storage Condition: Room temperature, sealed, dry
Product Description: Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antifungal and anticancer agents. Its structure supports the design of kinase inhibitors and bioactive molecules due to the electron-withdrawing trifluoromethyl group enhancing metabolic stability and membrane permeability. Also employed in agrochemicals for creating herbicides and pesticides, where the thiazole ring contributes to improved biological activity and selectivity. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidates.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1.000 10-20 days Ft3,005.37
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-
5.000 10-20 days Ft24,589.35
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-
4-(trifluoromethyl)thiazol-2-amine
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antifungal and anticancer agents. Its structure supports the design of kinase inhibitors and bioactive molecules due to the electron-withdrawing trifluoromethyl group enhancing metabolic stability and membrane permeability. Also employed in agrochemicals for creating herbicides and pesticides, where the thiazole ring contributes to improved biological activity and selectivity. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidates.
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