Tanshinone IIB
97%
- Product Code: 241442
CAS:
17397-93-2
| Molecular Weight: | 310.344 g./mol | Molecular Formula: | C₁₉H₁₈O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00238691 | |
| Melting Point: | Boiling Point: | 536.9±50.0℃ at 760 mmHg | |
| Density: | 1.3±0.1g/ml | Storage Condition: | 2-8℃, sealed, dried |
Product Description:
Tanshinone IIB is widely studied for its potential therapeutic applications in cardiovascular and cerebrovascular diseases. It exhibits strong anti-inflammatory and antioxidant properties, making it valuable in protecting heart tissue from ischemia-reperfusion injury. The compound has shown promise in inhibiting the progression of atherosclerosis by reducing oxidative stress and suppressing the inflammatory response in vascular endothelial cells.
In neurodegenerative research, Tanshinone IIB demonstrates neuroprotective effects, particularly in models of stroke and Alzheimer’s disease, where it helps reduce neuronal damage and improve cognitive function. It also displays antitumor activity by inducing apoptosis and cell cycle arrest in various cancer cell lines, including liver, breast, and lung cancers.
Additionally, Tanshinone IIB modulates several key signaling pathways such as PI3K/Akt, NF-κB, and MAPK, which are involved in cell survival, inflammation, and proliferation. Due to these multifaceted biological activities, it is considered a lead compound in the development of natural product-based drugs for chronic diseases.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 G | 10-20 days | ฿57,180.00 |
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Tanshinone IIB
Tanshinone IIB is widely studied for its potential therapeutic applications in cardiovascular and cerebrovascular diseases. It exhibits strong anti-inflammatory and antioxidant properties, making it valuable in protecting heart tissue from ischemia-reperfusion injury. The compound has shown promise in inhibiting the progression of atherosclerosis by reducing oxidative stress and suppressing the inflammatory response in vascular endothelial cells.
In neurodegenerative research, Tanshinone IIB demonstrates neuroprotective effects, particularly in models of stroke and Alzheimer’s disease, where it helps reduce neuronal damage and improve cognitive function. It also displays antitumor activity by inducing apoptosis and cell cycle arrest in various cancer cell lines, including liver, breast, and lung cancers.
Additionally, Tanshinone IIB modulates several key signaling pathways such as PI3K/Akt, NF-κB, and MAPK, which are involved in cell survival, inflammation, and proliferation. Due to these multifaceted biological activities, it is considered a lead compound in the development of natural product-based drugs for chronic diseases.
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