3-(4-((tert-butyldimethylsilyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
98%
- Product Code: 241765
| Molecular Weight: | 374.512 g./mol | Molecular Formula: | C₁₉H₂₆N₂O₄Si |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
Used in pharmaceutical synthesis as an intermediate in the development of targeted protein degradation therapies, particularly in the design of PROTACs (proteolysis-targeting chimeras). Its structure enables linkage between E3 ubiquitin ligase ligands and target protein binders, facilitating selective degradation of disease-related proteins. Commonly employed in research for oncology and neurodegenerative disease drug discovery due to its stability and modifiable functional groups. Also utilized in solid-phase synthesis and medicinal chemistry optimization for improved pharmacokinetic properties.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 0.100 | 10-20 days | £31.94 |
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| 0.250 | 10-20 days | £116.15 |
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| 1.000 | 10-20 days | £232.30 |
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3-(4-((tert-butyldimethylsilyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Used in pharmaceutical synthesis as an intermediate in the development of targeted protein degradation therapies, particularly in the design of PROTACs (proteolysis-targeting chimeras). Its structure enables linkage between E3 ubiquitin ligase ligands and target protein binders, facilitating selective degradation of disease-related proteins. Commonly employed in research for oncology and neurodegenerative disease drug discovery due to its stability and modifiable functional groups. Also utilized in solid-phase synthesis and medicinal chemistry optimization for improved pharmacokinetic properties.
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