tert-butyl (3,6,9,12-tetraoxapentadec-14-yn-1-yl)carbamate

90%

  • Product Code: 241976
  CAS:    1219810-90-8
Molecular Weight: 331.41 g./mol Molecular Formula: C₁₆H₂₉NO₆
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8℃
Product Description: Used as a bifunctional linker in bioconjugation and pharmaceutical synthesis, particularly in the preparation of antibody-drug conjugates (ADCs) and PEGylated compounds. The tert-butyl carbamate (Boc) group provides a protected amine that can be selectively deprotected under mild acidic conditions, allowing for controlled coupling to biomolecules. The terminal alkyne enables efficient conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC), commonly known as click chemistry, making it valuable in drug discovery, bioconjugation, and the development of diagnostic probes. Its polyether (PEG-like) spacer enhances solubility and improves pharmacokinetic properties of conjugated molecules.
Sizes / Availability / Pricing:
Size Availability Price Quantity
50mg 10-20 days ฿1,400.00
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250mg 10-20 days ฿4,140.00
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-
1g 10-20 days ฿15,600.00
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tert-butyl (3,6,9,12-tetraoxapentadec-14-yn-1-yl)carbamate
Used as a bifunctional linker in bioconjugation and pharmaceutical synthesis, particularly in the preparation of antibody-drug conjugates (ADCs) and PEGylated compounds. The tert-butyl carbamate (Boc) group provides a protected amine that can be selectively deprotected under mild acidic conditions, allowing for controlled coupling to biomolecules. The terminal alkyne enables efficient conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC), commonly known as click chemistry, making it valuable in drug discovery, bioconjugation, and the development of diagnostic probes. Its polyether (PEG-like) spacer enhances solubility and improves pharmacokinetic properties of conjugated molecules.
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