3-([(Tert-Butoxy)Carbonyl]Amino)Bicyclo[1.1.1]Pentane-1-Carboxylic Acid
97%
- Product Code: 242096
CAS:
303752-38-7
| Molecular Weight: | 227.260 g./mol | Molecular Formula: | C₁₁H₁₇NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09971715 | |
| Melting Point: | 172 °C | Boiling Point: | 370.4±41.0 °C at 760 mmHg |
| Density: | Storage Condition: | Room temperature, dry, sealed |
Product Description:
Used as a key building block in medicinal chemistry, particularly in the design of bioactive molecules and drug candidates. Its rigid bicyclopentane core serves as a bioisostere for phenyl or other aromatic rings, helping to improve metabolic stability, solubility, and reduce off-target effects. The presence of both Boc-protected amine and carboxylic acid functional groups allows for straightforward incorporation into peptide-like structures or further derivatization through standard coupling reactions. Frequently employed in fragment-based drug discovery and in the development of proteolysis-targeting chimeras (PROTACs) due to its favorable physicochemical properties and three-dimensional structure.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿1,720.00 |
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| 1g | 10-20 days | ฿3,920.00 |
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| 5g | 10-20 days | ฿9,880.00 |
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| 25g | 10-20 days | ฿46,000.00 |
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3-([(Tert-Butoxy)Carbonyl]Amino)Bicyclo[1.1.1]Pentane-1-Carboxylic Acid
Used as a key building block in medicinal chemistry, particularly in the design of bioactive molecules and drug candidates. Its rigid bicyclopentane core serves as a bioisostere for phenyl or other aromatic rings, helping to improve metabolic stability, solubility, and reduce off-target effects. The presence of both Boc-protected amine and carboxylic acid functional groups allows for straightforward incorporation into peptide-like structures or further derivatization through standard coupling reactions. Frequently employed in fragment-based drug discovery and in the development of proteolysis-targeting chimeras (PROTACs) due to its favorable physicochemical properties and three-dimensional structure.
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