3-(Trimethylsilyl)pyridin-2(1H)-one
95%
- Product Code: 242722
CAS:
17379-48-5
| Molecular Weight: | 167.28 g./mol | Molecular Formula: | C₈H₁₃NOSi |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD22056190 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of nitrogen-containing heterocyclic compounds. Its silyl group enhances reactivity and selectivity in cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex molecules. Commonly employed in palladium-catalyzed reactions to form carbon-carbon bonds, especially in the preparation of pyridine-based drug candidates. Also serves as a protecting group reagent due to the stability and easy removal of the trimethylsilyl moiety under mild conditions.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | £257.10 |
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| 250mg | 10-20 days | £436.68 |
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| 1g | 10-20 days | £1,178.63 |
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3-(Trimethylsilyl)pyridin-2(1H)-one
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of nitrogen-containing heterocyclic compounds. Its silyl group enhances reactivity and selectivity in cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex molecules. Commonly employed in palladium-catalyzed reactions to form carbon-carbon bonds, especially in the preparation of pyridine-based drug candidates. Also serves as a protecting group reagent due to the stability and easy removal of the trimethylsilyl moiety under mild conditions.
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