4-(((tert-butyldimethylsilyl)oxy)methyl)phenol

97%

  • Product Code: 242901
  CAS:    126070-20-0
Molecular Weight: 238.40 g./mol Molecular Formula: C₁₃H₂₂O₂Si
EC Number: MDL Number: MFCD29042407
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, sealed, dry
Product Description: Used as a protected form of a hydroxymethyl phenol in organic synthesis, particularly in the preparation of complex molecules where selective reactivity is required. The tert-butyldimethylsilyl (TBDMS) group shields the hydroxyl functionality, allowing other transformations to proceed without interference. It is commonly employed in multi-step syntheses of natural products, pharmaceuticals, and functional materials. The silyl ether can be selectively removed under mild conditions (e.g., using fluoride ions), restoring the free hydroxyl group when needed. Its stability under a variety of reaction conditions makes it valuable in building block strategies and in the synthesis of polyphenolic or glycosylated compounds.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days ฿1,390.00
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1.000 10-20 days ฿6,210.00
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5.000 10-20 days ฿26,890.00
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-
0.250 10-20 days ฿2,820.00
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4-(((tert-butyldimethylsilyl)oxy)methyl)phenol
Used as a protected form of a hydroxymethyl phenol in organic synthesis, particularly in the preparation of complex molecules where selective reactivity is required. The tert-butyldimethylsilyl (TBDMS) group shields the hydroxyl functionality, allowing other transformations to proceed without interference. It is commonly employed in multi-step syntheses of natural products, pharmaceuticals, and functional materials. The silyl ether can be selectively removed under mild conditions (e.g., using fluoride ions), restoring the free hydroxyl group when needed. Its stability under a variety of reaction conditions makes it valuable in building block strategies and in the synthesis of polyphenolic or glycosylated compounds.
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