1-(2,2,2-Trifluoroacetyl)indoline-5-sulfonyl chloride
97%
- Product Code: 243449
CAS:
210691-38-6
| Molecular Weight: | 313.68 g./mol | Molecular Formula: | C₁₀H₇ClF₃NO₃S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09261241 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, Inert Gas |
Product Description:
Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals and agrochemicals. Its sulfonyl chloride group enables easy attachment to amines or alcohols, forming sulfonamides or sulfonate esters, which are common motifs in drug design. The trifluoroacetyl group enhances electrophilicity and can act as a protecting group or be further transformed. It is especially valuable in the development of kinase inhibitors and other targeted therapies due to its ability to improve metabolic stability and binding affinity. Also employed in peptide modification and labeling due to its selective reactivity under mild conditions.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿5,440.00 |
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| 250mg | 10-20 days | ฿9,220.00 |
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| 1g | 10-20 days | ฿26,420.00 |
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1-(2,2,2-Trifluoroacetyl)indoline-5-sulfonyl chloride
Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals and agrochemicals. Its sulfonyl chloride group enables easy attachment to amines or alcohols, forming sulfonamides or sulfonate esters, which are common motifs in drug design. The trifluoroacetyl group enhances electrophilicity and can act as a protecting group or be further transformed. It is especially valuable in the development of kinase inhibitors and other targeted therapies due to its ability to improve metabolic stability and binding affinity. Also employed in peptide modification and labeling due to its selective reactivity under mild conditions.
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