5-(Trifluoromethyl)thiophene-2-sulfonyl chloride

95%

  • Product Code: 243616
  CAS:    954377-22-1
Molecular Weight: 250.65 g./mol Molecular Formula: C₅H₂ClF₃O₂S₂
EC Number: MDL Number: MFCD27934701
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, Inert Gas
Product Description: Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require fluorinated aromatic components. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamides and sulfonate esters—common motifs in drug design. Frequently employed in medicinal chemistry for modifying thiophene-based scaffolds to enhance metabolic stability and lipophilicity. Also applied in the preparation of functionalized polymers and specialty materials where fluorine substitution improves thermal and oxidative resistance.
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1g 10-20 days €2,134.59
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5-(Trifluoromethyl)thiophene-2-sulfonyl chloride
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require fluorinated aromatic components. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamides and sulfonate esters—common motifs in drug design. Frequently employed in medicinal chemistry for modifying thiophene-based scaffolds to enhance metabolic stability and lipophilicity. Also applied in the preparation of functionalized polymers and specialty materials where fluorine substitution improves thermal and oxidative resistance.
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