Tert-Butyl (1-(((S)-1-((R)-3-Benzyl-3-(1,2,2-Trimethylhydrazinecarbonyl)Piperidin-1-Yl)-3-(1H-Indol-3-Yl)-1-Oxopropan-2-Yl)Amino)-2-Methyl-1-Oxopropan-2-Yl)Carbamate
98%
- Product Code: 243896
CAS:
883572-59-6
| Molecular Weight: | 646.82 g./mol | Molecular Formula: | C₃₆H₅₀N₆O₅ |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in pharmaceutical research as a key intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs). It serves as a linker component that connects a target protein binder to an E3 ubiquitin ligase recruiter, enabling targeted protein degradation. Its tert-butyloxycarbonyl (Boc) protected amine group allows for controlled deprotection and further conjugation in multi-step synthetic routes. The structure supports solubility and stability during solid-phase or solution-phase peptide-like assembly, making it valuable in developing novel therapeutics for cancer, neurodegenerative diseases, and other conditions involving dysregulated proteins.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | £3,229.34 |
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Tert-Butyl (1-(((S)-1-((R)-3-Benzyl-3-(1,2,2-Trimethylhydrazinecarbonyl)Piperidin-1-Yl)-3-(1H-Indol-3-Yl)-1-Oxopropan-2-Yl)Amino)-2-Methyl-1-Oxopropan-2-Yl)Carbamate
Used in pharmaceutical research as a key intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs). It serves as a linker component that connects a target protein binder to an E3 ubiquitin ligase recruiter, enabling targeted protein degradation. Its tert-butyloxycarbonyl (Boc) protected amine group allows for controlled deprotection and further conjugation in multi-step synthetic routes. The structure supports solubility and stability during solid-phase or solution-phase peptide-like assembly, making it valuable in developing novel therapeutics for cancer, neurodegenerative diseases, and other conditions involving dysregulated proteins.
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