4,4,5,5-Tetramethyl-2-(4-(2,2,2-trifluoroethoxy)phenyl)-1,3,2-dioxaborolane

98%

  • Product Code: 244185
  CAS:    886528-42-3
Molecular Weight: 302.1 g./mol Molecular Formula: C₁₄H₁₈BF₃O₃
EC Number: MDL Number: MFCD22418017
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, sealed, dry, inert gas
Product Description: Used as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boron-containing structure facilitates coupling with aryl halides under palladium catalysis, making it valuable for constructing biaryl systems found in active pharmaceutical ingredients. The electron-withdrawing trifluoroethoxy group enhances reactivity and stability, improving coupling efficiency in complex molecule assembly. Commonly employed in late-stage functionalization due to its tolerance of various functional groups and reliable performance in both research and industrial settings.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.250 10-20 days $148.19
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1.000 10-20 days $471.56
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5.000 10-20 days $1,648.55
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0.100 10-20 days $86.64
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4,4,5,5-Tetramethyl-2-(4-(2,2,2-trifluoroethoxy)phenyl)-1,3,2-dioxaborolane
Used as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boron-containing structure facilitates coupling with aryl halides under palladium catalysis, making it valuable for constructing biaryl systems found in active pharmaceutical ingredients. The electron-withdrawing trifluoroethoxy group enhances reactivity and stability, improving coupling efficiency in complex molecule assembly. Commonly employed in late-stage functionalization due to its tolerance of various functional groups and reliable performance in both research and industrial settings.
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