Tert-butyl(S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate
98%
- Product Code: 244623
CAS:
483366-14-9
| Molecular Weight: | 232.23 g./mol | Molecular Formula: | C₁₀H₁₄F₂N₂O₂ |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in pharmaceutical synthesis as a chiral building block for developing protease inhibitors, particularly in the manufacture of antidiabetic drugs like DPP-4 inhibitors. Its fluorinated pyrrolidine structure enhances metabolic stability and binding selectivity. The tert-butoxycarbonyl (Boc) group protects the nitrogen during peptide coupling reactions, while the nitrile functionality allows further transformation into amides or tetrazoles. Commonly employed in asymmetric synthesis to introduce stereochemical control in active pharmaceutical ingredients (APIs).
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $270.30 |
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| 1.000 | 10-20 days | $900.33 |
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| 5.000 | 10-20 days | $3,394.74 |
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Tert-butyl(S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate
Used in pharmaceutical synthesis as a chiral building block for developing protease inhibitors, particularly in the manufacture of antidiabetic drugs like DPP-4 inhibitors. Its fluorinated pyrrolidine structure enhances metabolic stability and binding selectivity. The tert-butoxycarbonyl (Boc) group protects the nitrogen during peptide coupling reactions, while the nitrile functionality allows further transformation into amides or tetrazoles. Commonly employed in asymmetric synthesis to introduce stereochemical control in active pharmaceutical ingredients (APIs).
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