Tert-butyl(S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate

98%

Reagent Code: #244623
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CAS Number 483366-14-9

blur_circular Chemical Specifications

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Weight 232.23 g/mol
Formula C₁₀H₁₄F₂N₂O₂
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in pharmaceutical synthesis as a chiral building block for developing protease inhibitors, particularly in the manufacture of antidiabetic drugs like DPP-4 inhibitors. Its fluorinated pyrrolidine structure enhances metabolic stability and binding selectivity. The tert-butoxycarbonyl (Boc) group protects the nitrogen during peptide coupling reactions, while the nitrile functionality allows further transformation into amides or tetrazoles. Commonly employed in asymmetric synthesis to introduce stereochemical control in active pharmaceutical ingredients (APIs).

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿6,830.00
inventory 1g
10-20 days ฿22,750.00
inventory 5g
10-20 days ฿85,780.00
Tert-butyl(S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate
Used in pharmaceutical synthesis as a chiral building block for developing protease inhibitors, particularly in the manufacture of antidiabetic drugs like DPP-4 inhibitors. Its fluorinated pyrrolidine structure enhances metabolic stability and binding selectivity. The tert-butoxycarbonyl (Boc) group protects the nitrogen during peptide coupling reactions, while the nitrile functionality allows further transformation into amides or tetrazoles. Commonly employed in asymmetric synthesis to introduce stereochemical control in active pharmaceutical ingredients (APIs).
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