2-Propen-1-one,1-[4-(4-acetylphenyl)-1-piperazinyl]-3-[1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-,(2E)-
95%
- Product Code: 245615
CAS:
956949-45-4
| Molecular Weight: | 446.5 g./mol | Molecular Formula: | C₂₆H₂₇FN₄O₂ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 667.2±55.0 °C(Predicted) | |
| Density: | 1.21±0.1 g/cm3(Predicted) | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used in pharmaceutical research as a potent and selective inhibitor of phosphodiesterase 4 (PDE4), particularly targeting PDE4B and PDE4D isoforms. It demonstrates anti-inflammatory properties by reducing the production of pro-inflammatory cytokines such as TNF-α and IL-17, making it a candidate for treating autoimmune and inflammatory diseases like rheumatoid arthritis, psoriasis, and chronic obstructive pulmonary disease (COPD). Its structure allows for enhanced blood-brain barrier penetration, which supports investigation in neuroinflammatory conditions. Also employed as a biochemical tool in cellular assays to study cAMP signaling pathways and immune cell regulation.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25mg | 10-20 days | $393.39 |
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| 100mg | 10-20 days | $1,092.74 |
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2-Propen-1-one,1-[4-(4-acetylphenyl)-1-piperazinyl]-3-[1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-,(2E)-
Used in pharmaceutical research as a potent and selective inhibitor of phosphodiesterase 4 (PDE4), particularly targeting PDE4B and PDE4D isoforms. It demonstrates anti-inflammatory properties by reducing the production of pro-inflammatory cytokines such as TNF-α and IL-17, making it a candidate for treating autoimmune and inflammatory diseases like rheumatoid arthritis, psoriasis, and chronic obstructive pulmonary disease (COPD). Its structure allows for enhanced blood-brain barrier penetration, which supports investigation in neuroinflammatory conditions. Also employed as a biochemical tool in cellular assays to study cAMP signaling pathways and immune cell regulation.
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