N-[(4-ethoxy-3-methoxyphenyl)methyl]-N-methyl-2-(3-pyridinyl)-4-quinazolinamine
98%
- Product Code: 245663
CAS:
853339-68-1
| Molecular Weight: | 400.5 g./mol | Molecular Formula: | C₂₄H₂₄N₄O₂ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 507.0±50.0 °C(Predicted) | |
| Density: | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used in research as a potent and selective inhibitor of tyrosine kinases, particularly targeting epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2). These receptors are involved in signaling pathways that regulate cell proliferation and survival, making the compound valuable in studies of cancer biology. It has shown promise in preclinical models for inhibiting the growth of tumor cells, especially in non-small cell lung cancer and breast cancer. Its ability to cross the blood-brain barrier also makes it useful in investigating central nervous system metastases. Commonly employed in biochemical assays to elucidate kinase-dependent cellular mechanisms and as a lead compound in the development of targeted anticancer therapies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1mg | 10-20 days | $116.17 |
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| 25mg | 10-20 days | $1,866.16 |
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| 5mg | 10-20 days | $466.27 |
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N-[(4-ethoxy-3-methoxyphenyl)methyl]-N-methyl-2-(3-pyridinyl)-4-quinazolinamine
Used in research as a potent and selective inhibitor of tyrosine kinases, particularly targeting epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2). These receptors are involved in signaling pathways that regulate cell proliferation and survival, making the compound valuable in studies of cancer biology. It has shown promise in preclinical models for inhibiting the growth of tumor cells, especially in non-small cell lung cancer and breast cancer. Its ability to cross the blood-brain barrier also makes it useful in investigating central nervous system metastases. Commonly employed in biochemical assays to elucidate kinase-dependent cellular mechanisms and as a lead compound in the development of targeted anticancer therapies.
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