Wnt-C59 (C59)
10mM in DMSO
- Product Code: 245874
CAS:
1243243-89-1
| Molecular Weight: | 379.45 g./mol | Molecular Formula: | C₂₅H₂₁N₃O |
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| Density: | Storage Condition: | -20°C |
Product Description:
Wnt-C59 is a potent inhibitor of the Wnt signaling pathway, specifically targeting the porcupine enzyme, which is essential for the palmitoylation and activation of Wnt proteins. This compound is widely used in research to study the role of Wnt signaling in various biological processes, including embryonic development, tissue regeneration, and cancer progression.
One of its key applications is in oncology research, where it helps suppress the growth of cancer cells that depend on hyperactive Wnt signaling, such as in colorectal, liver, and breast cancers. By blocking Wnt ligand secretion, C59 effectively reduces tumor growth and cancer stem cell activity in preclinical models.
It is also used to investigate stem cell biology and tissue homeostasis, particularly in intestinal and skin models, where Wnt signaling plays a critical role in cell proliferation and differentiation. Due to its ability to modulate tissue regeneration, Wnt-C59 has been explored in fibrotic diseases and other conditions involving abnormal tissue growth.
Overall, Wnt-C59 serves as a valuable tool compound for understanding and potentially treating diseases driven by aberrant Wnt pathway activation.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | $396.57 |
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Wnt-C59 (C59)
Wnt-C59 is a potent inhibitor of the Wnt signaling pathway, specifically targeting the porcupine enzyme, which is essential for the palmitoylation and activation of Wnt proteins. This compound is widely used in research to study the role of Wnt signaling in various biological processes, including embryonic development, tissue regeneration, and cancer progression.
One of its key applications is in oncology research, where it helps suppress the growth of cancer cells that depend on hyperactive Wnt signaling, such as in colorectal, liver, and breast cancers. By blocking Wnt ligand secretion, C59 effectively reduces tumor growth and cancer stem cell activity in preclinical models.
It is also used to investigate stem cell biology and tissue homeostasis, particularly in intestinal and skin models, where Wnt signaling plays a critical role in cell proliferation and differentiation. Due to its ability to modulate tissue regeneration, Wnt-C59 has been explored in fibrotic diseases and other conditions involving abnormal tissue growth.
Overall, Wnt-C59 serves as a valuable tool compound for understanding and potentially treating diseases driven by aberrant Wnt pathway activation.
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