XMU-MP-1

10mM in DMSO

  • Product Code: 246044
  CAS:    2061980-01-4
Molecular Weight: 416.48 g./mol Molecular Formula: C₁₇H₁₆N₆O₃S₂
EC Number: MDL Number: MFCD30377214
Melting Point: Boiling Point:
Density: Storage Condition: -20°C
Product Description: XMU-MP-1 is a selective inhibitor of the mixed lineage kinase domain-like protein (MLKL), which plays a key role in the necroptosis pathway—a form of regulated cell death. Its primary application lies in research settings, where it is used to study the mechanisms of necroptosis and its involvement in various disease models. By inhibiting MLKL phosphorylation, XMU-MP-1 effectively blocks necroptotic cell death, making it a valuable tool for investigating inflammatory diseases, neurodegenerative disorders, ischemia-reperfusion injury, and tissue damage in conditions such as sepsis and acute kidney injury. It has also been used in preclinical studies to explore the therapeutic potential of targeting necroptosis in cancer and autoimmune diseases. Due to its cell permeability and specificity, XMU-MP-1 enables researchers to modulate necroptosis in cellular and animal models with high precision, supporting the development of novel therapeutic strategies.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1ml 10-20 days $510.81
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XMU-MP-1
XMU-MP-1 is a selective inhibitor of the mixed lineage kinase domain-like protein (MLKL), which plays a key role in the necroptosis pathway—a form of regulated cell death. Its primary application lies in research settings, where it is used to study the mechanisms of necroptosis and its involvement in various disease models. By inhibiting MLKL phosphorylation, XMU-MP-1 effectively blocks necroptotic cell death, making it a valuable tool for investigating inflammatory diseases, neurodegenerative disorders, ischemia-reperfusion injury, and tissue damage in conditions such as sepsis and acute kidney injury. It has also been used in preclinical studies to explore the therapeutic potential of targeting necroptosis in cancer and autoimmune diseases. Due to its cell permeability and specificity, XMU-MP-1 enables researchers to modulate necroptosis in cellular and animal models with high precision, supporting the development of novel therapeutic strategies.
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