YNT-185 dihydrochloride
≥98%(HPLC)
- Product Code: 246307
CAS:
1804978-82-2
| Molecular Weight: | 688.7 g./mol | Molecular Formula: | C₃₃H₃₉Cl₂N₅O₅S |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | -20°C |
Product Description:
Used in research settings as a potent and selective inhibitor of the menin-MLL (mixed lineage leukemia) protein-protein interaction, making it a valuable tool compound in studies targeting MLL-rearranged leukemias. It demonstrates strong anti-leukemic activity in cellular and animal models by disrupting oncogenic gene expression driven by the MLL fusion proteins. Due to its ability to cross the blood-brain barrier, it is also explored for potential activity against central nervous system involvement in leukemia. Primarily employed in preclinical research to validate menin inhibition as a therapeutic strategy and to guide the development of clinical candidates for acute leukemias.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿14,030.00 |
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| 0.025 | 10-20 days | ฿47,470.00 |
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YNT-185 dihydrochloride
Used in research settings as a potent and selective inhibitor of the menin-MLL (mixed lineage leukemia) protein-protein interaction, making it a valuable tool compound in studies targeting MLL-rearranged leukemias. It demonstrates strong anti-leukemic activity in cellular and animal models by disrupting oncogenic gene expression driven by the MLL fusion proteins. Due to its ability to cross the blood-brain barrier, it is also explored for potential activity against central nervous system involvement in leukemia. Primarily employed in preclinical research to validate menin inhibition as a therapeutic strategy and to guide the development of clinical candidates for acute leukemias.
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